alpha Fetoprotein anticorps
Aperçu rapide pour alpha Fetoprotein anticorps (ABIN7670527)
Antigène
Voir toutes alpha Fetoprotein (AFP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- alpha-Fetoprotein/AFP Monoclonal Antibody(Detector)
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Purification
- Protein A/G Purification
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Immunogène
- Human AFP Native Protein
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Isotype
- IgG1
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Indications d'application
- ELISA Detector 0.1-0.4 μg/mL
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Sterile PBS , pH 7.4
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C Valid for 1 month or -20°C Valid for 12 months
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Date de péremption
- 12 months
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Autre désignation
- alpha-Fetoprotein/AFP
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Sujet
- ALpha-fetoprotein,ALpha-1-fetoprotein,ALpha-fetogLobuLin,AFP,HPAFP,alpha-Fetoprotein (AFP),is albuminoid superfamily protein that is synthesized in the fetus primarily by the liver,yolk sac,and tissues of gastrointestinal origin. It is one of the earliest markers of the hepatocyte lineage. AFP acts as a carrier protein for steroids,bilirubin,fatty acids,retinoids,and flavonoids. In addition,it can exert immunosuppressive activity,regulate cell proliferation and apoptosis,initiate intracellular signaling,and contribute to cell invasion. Altered levels of both fetal and maternal AFP have been associated with hypothyroidism,autoimmune disorders,and heart defects. low maternal serum AFP levels are associated with a higher incidence of Down syndrome,whereas higher levels are associated with spina bifida and anencephaly. Elevated AFP levels are also coincident with liver,stomach,and germ cell cancers.
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UniProt
- P02771
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Pathways
- C21-Steroid Hormone Metabolic Process
Antigène
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